The aim of this study was to assess fungicidal and nematicidal potential of homeopathic pellets and globules on the improvement of plant growth in the management of plant pathogens. Amendment of homeopathic drug pellets and globules at 75 and 50% concentrations in soil suppressed the colonization of root infecting pathogens which alters the growth by increasing the height and weight of leguminous and non leguminous plants. However, using homeopathic globules in leguminous plants such as mung bean and mash bean gave negative effects by inhibiting nodules on the roots which was confirmed in vitro test. Homeopathic pellets of Kent-20 and Santonine-43 respectively, at both concentrations (75 and 50%) amended in soil improved the height and weight of plant but also suppressed the galls formation and egg masses on root system in leguminous and non leguminous plants. Amendment of homeopathic drug globules in non leguminous (sunflower and okra) plants only as it was already proved that it suppressed nodules formation in leguminous plant on root rot experiment, hence homeopathic drug globules showed pronounced effect on plant growth and reduced the infection caused by M. javanica. It was striking to observe in vitro test that when globules used without homeopathic drugs reduced the hatching of juveniles but failed to kill the nematode but when Kent-20 and Santonine-43 infused in globules, it exerted complete mortality at 96 hours in all concentrations (100, 75 and 50%). Field experiments were carried out on tested seeds treated with homeopathic pellets (A. montana, T. occidentalis, Kent-20 and Santonine-43) at 75 concentrations remarkably enhanced the plant growth and improved the crop yield but also control the plant pathogens.