Excellent performance at any stage in life is paramount to great achievement and good success at all levels of human endeavours including scholastic attainment. High academic performance requires thorough progressive guidance, adequate preparations through constant supervisions and mentoring from significant others which include but not limited to the learners, the teachers, school administrators, counselling psychologists and concerned parents. However, some learners are fraught with low academic performance and therefore would perform abysmally low. The low academic performance could be due to many factors. Internal factors within learners and external factors which could be positively managed to increase or activate high academic performance in the learners. This study therefore seeks to establish the synergy between the internal and external factors through effective mentoring to activate high academic performance in learners.