Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity

Background & Aims: The spectrum of soft illness} disease ranges from liver disease alone to soft steatohepatitis. Most previous studies have short follow-up and haven’t fastidiously depicted totally different microscopic anatomy sorts once crucial clinical outcomes. The aim of this study was to match clinical characteristics and outcomes of patients with differing types of soft liver disease. [1]

Nonalcoholic Fatty Liver Disease

Alcohol abuse is that the most typical explanation for liver {disease} disease, however it’s currently apparent that fat deposition within the liver, and its consequences, might occur while not drug abuse. The principal risk factors are blubber, ketosis-resistant diabetes mellitus, and lipoidemia. The disorder includes a wide clinical spectrum, starting from well steatosis to steatohepatitis, fibrosis, and cirrhosis of the liver. this text provides a broad summary of this more and more recognized disease. [2]

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

Nonalcoholic malady} disease (NAFLD) has been related to the insulin‐resistance syndrome, nowadays outlined because the metabolic syndrome, whose limits were recently set. we tend to assessed the prevalence of the metabolic syndrome in 304 consecutive NAFLD patients while not overt  polygenic disorder, on the premise of three or a lot of criteria out of five outlined by the U.S. National Institutes of Health (waist circumference, glucose, high‐density compound protein [HDL]‐cholesterol, triglycerides, and blood vessel pressure). [3]

Natural course of fatty liver in 36,195 South Korean adults

Nonalcoholic sickness} disease (NAFLD) is that the most typical reason for disease, and nevertheless the natural course remains unclear. Study population enclosed thirty six,195 people World Health Organization participated in a very health-screening program and diagnosed with liver disease by abdominal ultrasound. Participants were provided written info relating to liver disease and suggested to form style changes. Ultrasound was perennial once a minimum of vi months. [4]

Evaluation of High Levels of Triglycerides in Non-alcoholic Fatty Liver Disease

Non-alcoholic illness} disease (NAFLD) is beginning as accumulation of fat within the hepatocytes (steatosis) that could be a sub-clinical condition in those that don’t seem to be overwhelming alcohol. Non-alcoholic steatohepatitis (NASH) could be a condition of steatosis, related to inflammation of liver cell. this is often a clinical variety of NAFLD, that is considered a significant explanation for liver disease of the liver [1]. This distinction between straightforward steatosis and Ogden Nash is vital as a result of the explanation of those classes differs well. [5]


[1] Matteoni, C.A., Younossi, Z.M., Gramlich, T., Boparai, N., Liu, Y.C. and McCullough, A.J., 1999. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology, 116(6), pp.1413-1419. (Web Link)

[2] Angulo, P., 2002. Nonalcoholic fatty liver disease. New England Journal of Medicine, 346(16), pp.1221-1231. (Web Link)

[3] Marchesini, G., Bugianesi, E., Forlani, G., Cerrelli, F., Lenzi, M., Manini, R., Natale, S., Vanni, E., Villanova, N., Melchionda, N. and Rizzetto, M., 2003. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology, 37(4), pp.917-923. (Web Link)

[4] Natural course of fatty liver in 36,195 South Korean adults

Ki-Chul Sung, Mi-Yeon Lee, Jong-Young Lee, Sung-Ho Lee, Yong-Bum Kim, Won-Jun Song, Ji-Hye Huh, Jin-Sun Park, Jeong-Hun Shin, Mi Hae Seo, Seong-Hwan Kim & Sun H. Kim

Scientific Reportsvolume 9, Article number: 9062 (2019) (Web Link)

[5] Rao, D. S., Praveena, V. and Veeranna, B. (2018) “Evaluation of High Levels of Triglycerides in Non-alcoholic Fatty Liver Disease”, International Journal of Biochemistry Research & Review, 20(4), pp. 1-5. doi: 10.9734/IJBCRR/2017/33499. (Web Link)

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