News Update on Lipemia Research: Aug – 2019

News Update on Lipemia Research: Aug – 2019

News Update on Lipemia Research: Aug – 2019

Diabetic Lipemia — A Form of Acquired Fat-Induced Lipemia

DIABETIC lipidaemia (milky plasma), 1st represented within the nineteenth century, remains a well recognized however rare manifestation of uncontrolled DM. though prompt designation and hypoglycaemic agent treatment have in all probability reduced the incidence of lipoidaemia in symptomatic polygenic disorder, reports of this poorly understood syndrome still seem.1 a pair of 3>Since lipidaemia could also be related to variable degrees of supermolecule intolerance in an exceedingly wide spectrum of patients, the term “diabetic lipidaemia” are going to be restricted to explain the lipemia related to severe symptomatic polygenic disorder. This lipidaemia characteristically is abolished by hypoglycaemic agent treatment. The patient with this clinical syndrome ought to be pronto distinguished from the. [1]

Carbohydrate Intolerance and Lipemia

The association between supermolecule intolerance and lipemic disorders has been delineate and a pathophysiological classification developed. There seems to be very little proof for a cause-and-effect relation between supermolecule intolerance and endogenous hyperlipoidaemia (hypertriglyceridemia). One issue common to each, adiposity, might contribute to their frequent being. [2]

Postprandial lipemia, fenofibrate and coronary artery disease

This report describes the response of patients with severe arteria coronaria sickness to a dynamic fat load check and monitors the modification evoked by fenofibrate medical care. The presence of sickness was related to prolonged and exaggerated hypertriglyceridemia following the meal and with lower basal cholesterin and HDL subtraction lots. an extra indicator of risk was the persistence of exaggerated amounts of retinyl palmitate within the plasma of severely affected people twenty four h when its body process with the meal. These observations are in step with the proposal that the clearance of chylomicrons and their remnants is impaired in coronary induration of the arteries. [3]

Relationship between altered postprandial lipemia and insulin resistance in normolipidemic and normoglucose tolerant obese patients

OBJECTIVE: though there area unit changes within the postprandial supermolecule responses of fat patients, these area unit closely related to high fast triglycerides (TG). This study of seventeen normotriglyceridemic, normoglucose-tolerant golem fat subjects (body mass index, BMI=34.3±3.1 kg/m2) and thirty three normal-weight controls (BMI=21.8±1.6 kg/m2) was done to look at their postprandial responses to Associate in Nursing oral fat loading take a look at containing vitamin A1 (890 calories, eighty fifth fat) and to guage the doable association between clinical and biological options of fatness and/or hypoglycemic agent resistance and postprandial lipoidemia. [4]

Portulaca oleracea Reduces Lipemia, Glycemia, and Oxidative Stress in Streptozotocin-induced Diabetic Rats Fed Cholesterol-enriched Dietq

Aims: during this study, the results of common purslane (Po) within the treatment of hypercholesteremia combined with polygenic disorder in rats were investigated.

Place and length of Study: Laboratory of Clinical and Metabolic Nutrition, Department of Biology, Nature and Life Sciences college, University of Oran1, Algeria, between Sep and July 2017.

Study Design: the results of associate degree liquid extract from the leaves of Po were studied on aldohexose equilibrium, supermolecule parameters, and aerophilous stress markers, in streptozotocin (STZ) induced  diabetic rats on a cholesterol-enriched diet. [5]

Reference

[1] Bagdade, J.D., Porte Jr, D. and Bierman, E.L., 1967. Diabetic lipemia: a form of acquired fat-induced lipemia. New England Journal of Medicine, 276(8), pp.427-433. (Web Link)

[2] BIERMAN, E.L. and PORTE, D., 1968. Carbohydrate intolerance and lipemia. Annals of Internal Medicine, 68(4), pp.926-933. (Web Link)

[3] Simpson, H.S., Williamson, C.M., Olivecrona, T., Pringle, S., Maclean, J., Lorimer, A.R., Bonnefous, F., Bogaievsky, Y., Packard, C.J. and Shepherd, J., 1990. Postprandial lipemia, fenofibrate and coronary artery disease. Atherosclerosis, 85(2-3), pp.193-202. (Web Link)

[4] Relationship between altered postprandial lipemia and insulin resistance in normolipidemic and normoglucose tolerant obese patients
B Guerci, B Vergès, V Durlach, S Hadjadj, P Drouin & J-L Paul
International Journal of Obesityvolume 24, pages468–478 (2000) (Web Link)

[5] Djellouli, F., Krouf, D., Lacaille-Dubois, M. A. and Bouchenak, M. (2018) “Portulaca oleracea Reduces Lipemia, Glycemia, and Oxidative Stress in Streptozotocin-induced Diabetic Rats Fed Cholesterol-enriched Dietq”, Journal of Pharmaceutical Research International, 23(4), pp. 1-12. doi: 10.9734/JPRI/2018/43495. (Web Link)

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