Assessing the Impact of Iron Deficiency Anemia Treatment on Type 2 Diabetic Complications

Assessing the Impact of Iron Deficiency Anemia Treatment on Type 2 Diabetic Complications

The study was aimed to evaluate the relationship between the iron deficiency anemia (IDA) and type

2 diabetes, to estimate the effect of the IDA on the level of glucose and glycated hemoglobin (Hb1Ac)

and to assess the ameliorating effect of IDA treatment on progression of diabetes and its

complications. This study included 125 male Fasting blood glucose (FBG), HbA1c, CBC, ferritin, iron,

and total iron binding capacity (TIBC) were assayed. The HbA1c and FBG levels were significantly

higher in groups III and IV compared to group I. The results revealed a significant decline in HbA1c

and FBG levels in group V compared to group IV. Negative significant correlations were observed

between iron and ferritin with HbA1c and FBG. Ferritin was the most reliable predictor of type 2

diabetes in patients with IDA. The best cut off value for ferritin was 31.56 ng/ml. Low iron level has a

crucial effect on glycemic status by increasing the level of FBG and HbA1c, IDA is strongly correlated

with type 2 diabetes and the iron supplementation for diabetic patients with IDA ameliorates the

progression of diabetes and its complications.

 

Author (s) Details

 

Amira S. Ahmed

Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Qassim, Saudi Arabia and Hormones Department, Medical Research Division, National Research Centre, Giza, Egypt.

Rehab M. Elgharabawy

Department of Pharmacology and Toxicology, College of Pharmacy, Qassim University, Qassim, Saudi Arabia and Pharmacology and Toxicology Department, Faculty of Pharmacy, Tanta University, Egypt.

Amal H. Al-Najjar

Drug and Poison Information Specialist, Pharmacy Services, Security Forces Hospital, Riyadh, Saudi Arabia.

Monerh H. Al-Abdullatif

College of Pharmacy, Qassim University, Qassim, Saudi Arabia.

Mona A. Al-Abdullatif

College of Pharmacy, Qassim University, Qassim, Saudi Arabia.

Turki A. Al-Mogbel

Buraydah Diabetes Center, King Fahad Specialist Hospital, Saudi Arabia.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/239

 

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