HMB Supplementation and Resistance Training: Current Overview on Inflammation, Oxidative Stress and Cardiovascular Risk Factors

HMB Supplementation and Resistance Training: Current Overview on Inflammation, Oxidative Stress and Cardiovascular Risk Factors

The bioactive metabolite of the branched-chain amino acid leucine, -hydroxy-methylbutyrate (HMB), is a common dietary supplement among athletes who engage in daily resistance training for muscle gain and strength. HMB, on the other hand, has gotten less publicity for its effects on inflammation, oxidative stress (OS), and cardiovascular risk factors after resistance exercise. As a consequence, the purpose of this chapter is to provide a logical overview of the current literature in this field. Because of the limited number of studies that have been conducted, the findings should be viewed with caution. The evidence reviewed here, however, suggests that acute HMB supplementation can reduce the pro-inflammatory response in athletes following high-intensity resistance exercise. Furthermore, the available evidence indicates that chronic HMB consumption combined with resistance training does not boost cardiovascular parameters or OS markers any more than resistance training alone. Overall, more well-designed, long-term studies are needed to support these findings and determine whether HMB supplementation affects resistance training-induced adaptations in the body’s inflammatory state, cardiovascular health, and antioxidative defence system in humans.

Author (s) Details

Hamid Arazi
Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht 4199843653, Iran.

Behzad Taati
Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht 4199843653, Iran.

Katsuhiko Suzuki
Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan.

View Book :- https://stm.bookpi.org/RRAB-V5/issue/view/36

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