Latest Research News on Pulmonary Artery: Jan – 2020

Latest Research News on Pulmonary Artery: Jan – 2020

Latest Research News on Pulmonary Artery: Jan – 2020

CT-determined pulmonary artery diameters in predicting pulmonary hypertension.

This study was to work out if the diameters of pulmonary arteries measured from computed tomographic (CT) scans might be used 1) as indicators of arteria pulmonalis hypertension and 2) as a reliable base for calculating mean arteria pulmonalis pressure. The diameters of the most , left, proximal right, distal right, interlobar, and left descending pulmonary arteries were measured from CT scans in 32 patients with cardiopulmonary disease and in 26 age- and sex-matched control subjects. Diameters were measured employing a special computer virus that would display a CT density profile of the artery and its adjacent tissues. The upper limit of normal diameter for the most arteria pulmonalis was found to be 28.6 mm (mean + 2 SD). within the patient group, the diameters were correlated with data from cardiac catheterization. In these patients, a diameter of the most arteria pulmonalis above 28.6 mm readily predicted the presence of pulmonary hypertension. [1]

Transplantation of a Tissue-Engineered Pulmonary Artery

To the Editor: Various vascular grafts are commonly utilized in the reconstruction of cardiovascular tissues. However, prosthetic or bioprosthetic materials lack growth potential and thus in children require replacement because the children grow. Tissue engineering offers the potential to make replacement structures from autologous cells and biodegradable polymer scaffolds. Since they contain living cells, these structures have the potential to grow, to repair themselves, and to transform themselves.14 A four-year-old girl had been found to possess one ventricle and pulmonary atresia and had undergone pulmonary-artery angioplasty and therefore the Fontan procedure at the age of three years, three. [2]

Prognostic value of pulmonary artery pressure in chronic obstructive pulmonary disease.

In 175 patients with chronic obstructive lung disease (157 chronic bronchitic and 18 emphysematous patients) exhibiting moderate to severe airway obstruction (mean FEV1/vital capacity = 40.2 11.1%), cumulative survival rates calculated by the actuarial method were compared in subgroups consistent with the initial level of mean arteria pulmonalis pressure, pulmonary volumes, and blood gases. Patients were catheterised between 1968 and 1972 and were followed for a minimum of five years. The results emphasise the high prognostic value of PAP since survival rates after four and 7 years were significantly lower within the subgroup with PAP greater than 20 mmHg (2.7 kPa). Certain other parameters (“driving” pressure across the circulation , FEV1 and Paco2) appear to be equally good at predicting survival as PAP in these obstructed patients. [3]

Health risk stratification based on computed tomography pulmonary artery obstruction index for acute pulmonary embolism

Early effective identification of high-risk patients for acute embolism (APE) contributes to timely treatment. The arteria pulmonalis obstruction index (PAOI) in computerized tomography angiography (CTA) may be a semi-quantitative observation index, commonly wont to evaluate the severity of a patient’s condition. This study explores the power of PAOI to assess the danger stratification of APE. Thirty patients with APE were analysed. They were classified consistent with the rules , and therefore the PAOI and cardiovascular parameters were measured in CTA. The difference of PAOI between different risk stratification patients was compared, and therefore the predictive value of the PAOI for high-risk stratification was evaluated by the receiver operating characterisic function. [4]

Coexistence of Sarcoidosis and Tuberculosis Presenting with Severe Pulmonary Artery Hypertension: A Clinical Dilemma

Background: Chronic granulomatous conditions affecting the systema respiratorium like tuberculosis and sarcoidosis have similar case presentations suggesting them to be polar ends of an equivalent disease spectrum thus putting physicians into a clinical dilemma. This case report highlights one such unique presentation.

Case Presentation: A young female, presented with respiratory distress and significant weight loss. Investigations showed severe arteria pulmonalis hypertension (PAH), kidney failure and generalized lymphadenopathy suggesting multisystem involvement. The initial diagnosis was sarcoidosis warranting corticosteroids but since Mantoux test suggested tuberculosis we were during a dilemma regarding therapeutic options. [5]

Reference

[1] Kuriyama, K.E.I.K.O., Gamsu, G.O.R.D.O.N., Stern, R.G., Cann, C.E., Herfkens, R.J. and Brundage, B.H., 1984. CT-determined pulmonary artery diameters in predicting pulmonary hypertension. Investigative radiology, 19(1), (Web Link)

[2] Shin’oka, T., Imai, Y. and Ikada, Y., 2001. Transplantation of a tissue-engineered pulmonary artery. New England Journal of Medicine, 344(7), (Web Link)

[3] Weitzenblum, E., Hirth, C., Ducolone, A., Mirhom, R., Rasaholinjanahary, J. and Ehrhart, M., 1981. Prognostic value of pulmonary artery pressure in chronic obstructive pulmonary disease. Thorax, 36(10), (Web Link)

[4] Health risk stratification based on computed tomography pulmonary artery obstruction index for acute pulmonary embolism
Fei Guo, Guanghui Zhu, Junjie Shen & Yichuan Ma
Scientific Reports volume 8, (Web Link)

[5] Bhagwat, B. and Thyagaraj, V. (2018) “Coexistence of Sarcoidosis and Tuberculosis Presenting with Severe Pulmonary Artery Hypertension: A Clinical Dilemma”, Journal of Advances in Medicine and Medical Research, 26(7), (Web Link)

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