Implementing One Health Concept in Rural Communities of Sierra Leone

The study’s goal is to bring rural residents together to combat rabies in their communities. In most rural areas of developing countries, where health care delivery is still a mirage, one health issue must be embraced and adequately implemented. The problems and approaches of implementing one health concept in Sierra Leone’s rural communities are examined in this study. Invitees, Non-Governmental Organizations operating in communities, direct and indirect beneficiaries in and around the project area, including officials from the government, were surveyed using a rapid and participatory rural assessment method. District Council members, councillors, ward representatives, Paramount Chiefs, community leaders, health workers, International and National Non-Governmental Organizations, Traders, Animal Owners, and Ministry of Health and Agriculture officials Due to a multitude of factors, including a shortage of qualified available workers, insufficient infrastructure, and a weak health system in the animal and human sectors, adopting One Health in this type of rural community has proven problematic. as well as financial mismanagement and a lack of well-organized organisations. It also emphasised the importance of one-health needs and relevant zoonotic illnesses as a starting point for putting the one-health concept into action. Rabies is one of the zoonoses discovered, and it has been identified as a factor that must be improved in order to achieve rabies control in rural regions.

Author (S) Details

Dr. R. Suluku
Animal Science Serology and Molecular Diagnostic Laboratory, Njala University, Sierra Leone.

A. T. Jalloh
Ministry of Agriculture Forestry and Food Security, Sierra Leone.

Prof. B. O. Emikpe

Department of Veterinary Pathology, University of Ibadan, Nigeria.

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Molecular Analysis of CYP21A2 Gene Mutations among Congenital Adrenal Hyperplasia Patients in Iraq

A category of autosomal recessive illnesses known as congenital adrenal hyperplasia. 21-hydroxylase insufficiency is the most common. Iraq has yet to report on the analysis of CYP21A2 gene mutations. The goal of this study is to look at the range and frequency of CYP21A2 mutations in Iraqi CAH patients. From September 2014 to June 2015, sixty-two children were recruited from the Pediatric Endocrine Consultation Clinic at the Children Welfare Teaching Hospital in Baghdad, Iraq. Their ages ranged from one day to fifteen years. Salt wasting, simple virilization, or pseudoprecocious puberty were all symptoms. For instances with ambiguous genitalia, a cytogenetic analysis was carried out. The CYP21A2 gene has been studied at the molecular level. >50% of significant gene deletions/conversions are caused by mutations. Patients with mutations were detected in 42 (67.7%) of cases; 31 (50%) were homozygotes, 9 (14.5%) were heterozygotes, and 2 (3.2%) were compound heterozygotes with three mutations, while 20 (32.3%) had none of the mutations evaluated. Large gene deletions/conversions were the most common mutations, with 12 (19.4%) patients having them, followed by I2Splice and Q318X with 8 (12.9%) patients each, I172N with 5 (8.1%) patients, and V281L with 4 (6.5%) patients. Del 8 bp, P453S, and R483P were all discovered in one sample (1.6 percent ) In two cases, complicated alleles were discovered (3.2 percent ). There were no point mutations found in any of the patients (P30L, Cluster E6, L307 frameshift, and R356W). Finally, gene deletions/conversions and 7 point mutations were found in varied amounts, with the former being the most common, which is consistent with what has been reported in other regions.

Author (S) Details

Dr. Ruqayah G. Y. Al-Obaidi
Genetic Counseling Clinic and Genetics Laboratory, The Teaching Laboratories, Medical City, Baghdad, Iraq.

Assist. Professor Dr. Bassam
Department of Pathology, College of Medicine, University of Baghdad, Baghdad, Iraq.

Professor Dr. Munib Ahmed K. AlZubaidi
Department of Pediatrics, College of Medicine, University of Baghdad and Pediatric Endocrine Consultation Clinic, Children Welfare Hospital, Baghdad, Iraq.

Dr. Christian Oberkanins
ViennaLab Diagnostics GmbH, Gaudenzdorfer Guertel 43-45, 1120 Vienna, Austria.

Stefan Németh
ViennaLab Diagnostics GmbH, Gaudenzdorfer Guertel 43-45, 1120 Vienna, Austria.

Yusra G. Y. Al-Obaidi
National Center of Hematology, Al-Mustansiriya University, Baghdad, Iraq.

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The Impact of Bioresonance Therapy on Human Health

Introduction: Bioresonance is a holistic physical technique that can be used to diagnose and treat a variety of illnesses. The electromagnetic waves received from the patient are used by bioresonance. This biophysical treatment modifies the energy field of the diseased body, improving the autoimmune system’s effectiveness and hence the patient’s general health. Bioresonance isn’t a cure-all, and it’s not meant to take the place of traditional treatment. The researchers utilised a quasi-experimental method to see if bioresonance had an influence on the patients’ symptoms. The examination of numerous characteristics such as age, gender, studies, occupation, intolerance or disease, as well as the existence and balancing of allergic charges, are all part of statistical data processing. 311 patients from doctors and bio-coordinating laboratories in Athens, Thessaloniki, Volos, and Xanthi participated in the study. The study’s participants ranged in age from 2 to 76 years old and included both men (120 subjects – 38.58 percent) and women (191 subjects – 61.42 percent). Patients between the ages of 31 and 45 had the highest number of patients. The individuals with nose symptoms (61.09 percent) were the most common, followed by ocular, respiratory, cutaneous, and gastrointestinal complaints. After a year of bioresonance treatment, the majority of patients (90 percent) report no symptoms or significant improvement in their symptoms. These findings suggest that bioresonance intervention had a significant effect on symptom improvement, and that this improvement is still visible 12 months later; p.01. Conclusion: We hope that the upcoming findings will contribute to a greater knowledge of bioresonance’s effect on the human body, as well as its role in avoiding and resolving health problems. Bioresonance is a relatively new concept in medicine that addresses the need for early diagnosis of abnormalities and organ malfunctions that could lead to illnesses.

Author (S) Details

Periklis Karakos
School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Tripsiannis Grigorios
School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Konstantinidis Theodoros
School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

Lialiaris Theodoros
School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

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Studies on Early Infantile Gangliosidosis GM

Gangliosidosis is described as the accumulation of Glycosphingolipids (Gangliosides) as a result of a defective enzyme or its stimulating factors impairing its metabolism. On the outer membrane of neurons, sialylated glycosphingolipids are particularly prevalent. Glycosphingolipids or their catabolites have been implicated in cell differentiation and morphogenesis in a number of investigations. genesis. The disease’s prognosis is mostly determined by residual -hexosaminidase activity, pre-polypeptide chain mRNA, and the status of the HEXB gene. The HEXB gene, on the other hand, is responsible for the majority of the primary gene deficiency. Early infantile gangliosidosis has an aetiology and pathophysiology that are currently unknown. Because it is an autosomal recessive condition, pre-marital screening of individuals can reduce the disease’s incidence.

Author (S) Details

Hamaiyal Sana
Bolan Medical College Quetta, Balochistan, Pakistan.

Abdul Qahar Khan Yasinzai
Bolan Medical College Quetta, Balochistan, Pakistan.

Noorain Baloch
Bolan Medical College Quetta, Balochistan, Pakistan.

Janita Zarrish
Bolan Medical College Quetta, Balochistan, Pakistan.

Fida Mengal
Bolan Medical College Quetta, Balochistan, Pakistan.

Muhammad Samsoor Zarak
Bolan Medical College Quetta, Balochistan, Pakistan.

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Factors Influencing Uptake of Focused Ante Natal Care in Kenya a Case Study of Nyatoto Community

The third sustainable target (UN 2015) is for a decrease of 70 maternal deaths per 100,000 women. Despite the fact that maternal mortality has decreased dramatically in Africa, many nations still have high maternal mortality rates. Kenya’s death rate has dropped dramatically, from 488 fatalities per 10,000 in 2016 to 350 deaths per 100,000 in 2017. Women’s health is a significant predictor of a country’s overall economic health and well-being. The survival of babies is inextricably tied to maternal health. FANC (Focused Antenatal Care) is a commonly utilised method for improving the health of pregnant women. pregnant people and to promote excellent delivery care. Kenya’s Ministry of Health produced a national adaptation plan in 2011 based on the World Health Organization’s new model (WHO) The factors impacting FANC uptake in the Nyatoto sub-location of Kenya’s HomaBay County were investigated in this cross-sectional study. Nyatoto village is a small rural village in Kenya’s western region. The study used a stratified systemic sampling strategy and an analysis of variance. To collect data, set up an interview schedule. All of the participants were found to be eligible based on predefined criteria. Microsoft Excel was used to examine the data. According to the findings, 23.6 percent of the participants had previously experienced a miscarriage. Malaria was the most common cause (30.7 percent ). The majority of women (85.5%) favoured hospital delivery, whereas only 14.5 percent preferred home delivery, citing unpleasant health staff and a lack of understanding of the value of hospital delivery as reasons. Women make up 47.3 percent of the population in the United States. The Nyatoto community used to have a home delivery service. In order to improve FANC services, the study suggested a collaborative strategy involving health care practitioners, FANC mothers, and the community at large. Improved FANC services will help mothers get the most out of their care. Furthermore, the ministry of education, county governments, and other development partners should also contribute to adult education programmes. Women with little or no education should be encouraged to enrol.

Author (S) Details

David K. Njeru
Department of Community Health, Egerton University, Kenya.

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Effectiveness of Music Video on HIV/AIDS Prevention among Female Factory Workers in Lao PDR

Background: In the Lao PDR, rapid socioeconomic development has resulted in significant changes in young people’s lifestyles and sexual behaviour. Because school-based HIV/AIDS education is insufficient, effective educational techniques must be developed. The goal of this study was to create and assess an Entertainment-Education Music Video (EEMVL) using ‘Lam,’ a Lao traditional folk song. The experiment was carried out in a plant in the southern region of Laos. Factory workers were educated about HIV/AIDS by viewing EEMVL. 51 female manufacturing workers completed semi-structured questionnaires before and after the intervention, as well as at a two-week follow-up. The questionnaire asked about HIV/AIDS knowledge and awareness, condom use self-efficacy, condom use intention, and positive and negative attitudes toward HIV/AIDS patients. From pre-intervention to two-week follow-up, the results revealed higher condom usage self-efficacy (p0.001), decreased negative attitudes toward persons living with HIV/AIDS (p=0.003), and improved HIV/AIDS information communication among factory workers (p0.001). The intention to use condoms increased from pre to post (p=0.017), but declined two weeks later (p=0.02). The drop in intention was attributable to the participant’s recognition of the significance ofhaving the knowledge and skills to protect oneself from HIV infection, and understanding that condoms do not provide 100% protection against HIV infection Furthermore, the participants stated a wish to protect Lao culture from HIV/AIDS and to carry out their responsibilities as Lao citizens. Conclusion: These findings revealed that the audience’s health literacy on HIV/AIDS prevention improved as a result of the social modelling behaviour displayed in the EEMVL, and that interpersonal contact among the participants was stimulated.

Author (S) Details

Itsuko Yoshida
Department of Nursing, Yasuda Women’s University, Japan.

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COVID-19 Pandemic Preparedness and Control Measures by India: The Nationwide Lockdown and Impact

The year 2019 was drawing to a close, and a new coronovirus would usher in the New Year. COVID-19, a new Coronavirus, was declared a PHEIC and then a Pandemic on March 11th, 2020. The disease’s symptoms are similar to those of the flu (influenza) or a common cold, both of which are significantly more common than COVID-19. In more serious cases, an infection may show as pneumonia or abrupt onset dyspnea, with transmission occurring through direct contact with respiratory droplets. The Indian government was important in swift action from the time this illness was simply an epidemic and had yet to be declared a pandemic. The Indian government (GOI) began taking initiatives to improve the situation. Screening of international travellers, surveillance through the IDSP network, 14-day entry quarantine, suspension of entry of any foreign nationals from the PRC, establishment of a control room, and other measures are being taken to postpone the inevitable outcome and buy time for the health department to implement mitigation measures. The Government of India had proactively responded to the ‘Test, Track, and Treat’ plan. It included expanding lab facilities, including the business sector, declaring masks and sanitizers as vital commodities, establishing RRTs in states, testing at the most number of places possible, contact tracing of positives, and active monitoring in a select areas of the country. India has learned a valuable lesson. Learning from other nations, the social vaccine was adopted as a temporary remedy until the vaccine was available. The benefits of non-pharmacological therapies were recognised and disseminated to the general public through a variety of IEC initiatives. All of these steps were performed prior to the enactment of the ‘LOCKDOWN’ on March 24, 2020. Although the lockdown had many unintended repercussions, the GOI saw it as the only preventive step available to stem the tide. The lockdown had no effect on the delivery of life-saving medical services. All government and private health care facilities were inspected. The social vaccination was adopted as a temporary treatment until the vaccine was ready, based on lessons learned from other countries. Through a number of IEC activities, the benefits of non-pharmacological therapy were recognised and conveyed to the general public. Prior to the enactment of the ‘LOCKDOWN’ on March 24, 2020, all of these stages were completed. The GOI saw the lockdown as the only preventive measure available to stem the tide, despite its many unforeseen consequences. The lockdown had no impact on the provision of life-saving medical assistance. All health-care facilities, both public and private, were inspected.

Author (S) Details

Dr. Saurabh Rattan
CMO Office, Kangra, Himachal Pradesh, India.

Dr. Anmol Gupta,
Department of Community Medicine, IGMC, Shimla, India.

Dr. Gopal Ashish Sharma
Department of Community Medicine, IGMC, Shimla, India.

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Studies on the Occurrence of Geohelminths amongst Children and Young Adults in Ovia NorthEast LGA of Edo State, South-South, Nigeria

The infection of children and young people with parasitic worms was studied in three schools in the Ovia North East Area of Edo State, Nigeria. Physical and parasitological methods of examining faecal material were used to determine positive cases. A total of 1072 people out of 2,045 were found to have helminth parasites (parasitic worms). Ascaris parasites were discovered. Strongylloides stecoralis (N=211), Taenia sp (N=111), Trichuris trichuria (N=278), and Ancylosloma duodenele (N=487) were among the species studied. The overall infection rate was 52.4 percent, with children aged 9-11 years having the highest prevalence and severity of infections (63.0 percent; 641 parasites), followed by those aged 6-8 years (61.1 percent; 526 parasites). Males had considerably greater rates of infection (57.7%) than females (47.3%) (P0.05).

Author (S) Details

Okafor-Elenwo, Ebere Julein
Department of Biological Sciences, Igbinedion University, Okada, Nigeria.

Izevbuwa Osazee Ekundayo
Department of Biological Sciences, Igbinedion University, Okada, Nigeria.

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Studies on the Use of Bone Growth Stimulators in the Treatment of Knee Osteoarthritis

The Use of Bone Growth Stimulators in the Treatment of Knee Osteoarthritis Background: The goal of this research was to explore if using Ultrasound Bone Growth Stimulators for knee osteoarthritis was beneficial. There is evidence that osteoarthritis of the knee is primarily a subchondral bone disease accompanied with joint changes. Osteoarthritis of the knee may be treated with bone growth stimulators because it contains fibrous tissue in the subchondral bone, and bone growth stimulators function by transforming fibrous tissue in the callus of fracture nonunion into normal bone. The participants in this pilot trial were ten patients with verified osteoarthritis of the knee. Before and after therapy with noninvasive bone growth stimulators, each patient’s pain and quality of life were rated on three different scales. A total of eight patients were treated with ultrasound, one with pulsed electromagnetic fields, and one with combined magnetic fields. Nine of the eleven statistical tests performed on three different scales for ultrasound had a high level of significance. The complete scores on all three assessment scales improved by more than 80% for the participants who were treated with pulsed electromagnetic fields and combined magnetic fields.
On three separate scales for ultrasound, nine of the eleven statistical tests exhibited a high level of significance. The subjects who were treated with pulsed electromagnetic fields and coupled magnetic fields increased their overall scores on all three evaluation scales by more than 80%.

Author (S) Details

Dr. Breanna Willeford
Alabama College of Osteopathic Medicine, USA.

Sierra Willeford
Edward Via College of Osteopathic Medicine- Carolinas Campus, USA.

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Focusing on Medication Errors Related to High Alert Medication

The goal of this research was to compare the trend of medication errors caused by high alert medications before and after the implementation of revised high alert medication strategies. Methods: From January to April 2017, data on medication errors was collected, and high alert medicines were found to be the source of medication errors. The rate of high-alert drug errors was analysed and determined. Develop and re-implement techniques in the medication management process. Methods: From January to April 2017, data on medication errors was collected, and medication errors induced by high alert medicines were detected. The rate of high-alert drug errors was studied and determined. Develop and re-implement techniques in the medicine administration procedure. Data on high-alert medication errors was collected from May to August 2017. The incidence and severity of high-alert drug mistakes were calculated. The frequency of high alert medication mistakes was dramatically reduced after developing and implementing a high alert medication mistake avoidance plan. Conclusion: It has been demonstrated that the suggested techniques for preventing high-alert medication errors reduce high-alert medication errors. However, the high prevalence of warning medication errors should be continuously monitored, and solutions should be examined for efficacy on a regular basis.

Author (S) Details

Nipul Kapadia
Apollo Hospitals International Limited, Ahmadabad, India.

Sachin Raval
Apollo Hospitals International Limited, Ahmadabad, India.

Parag Gadhave
Apollo Hospitals International Limited, Ahmadabad, India.

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