Assessment and Evaluation of DPPH Radical Scavenging Activity of 2-(Furan-2′-yl)-3-hydroxy-4Hchromen-4-one and Their Derivatives

Assessment and Evaluation of DPPH Radical Scavenging Activity of 2-(Furan-2′-yl)-3-hydroxy-4Hchromen-4-one and Their Derivatives

The 2-(furan-2′-yl)-3-hydroxy-4H-chromen-4-one and their substituted derivatives have been synthesised with electron donating and electron withdrawing classes. The activity of free radical scavenging was studied using 22′-diphenyl-1-picrylhydrazine (DPPH). The effect of these groups on percentage scavenging behaviour is explained by kinetic studies and the co-relation of excited state intramolecular proton transfer (ESIPT) with the electron donating and electron withdrawing group. Experimental studies show that a number of factors depend on the percentage of scavenging activity. Time and replacement effects that modify the function of antioxidants have been studied in this piece of work. The 2- and 6-position replacement affects the molecule’s electron density and dipole moment, due to which ESIPT interactions and antioxidant activity differ. Different parameters that influence both ESIPT and percent scavenging together need to be researched further.

Author(s) Details

Ranbir Kaur
Department of Chemistry, Punjabi University, Patiala-147 002, India.

Kulvir Kaur
Department of Chemistry, Punjabi University, Patiala-147 002, India.

Dr. Manisha Bansal
Department of Chemistry, Punjabi University, Patiala-147 002, India.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/354

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