Latest Research News on oral cavity: Feb – 2020

Latest Research News on oral cavity: Feb – 2020

Defining the Normal Bacterial Flora of the Oral Cavity

More than 700 bacterial species or phylotypes, of which over 50% have not been cultivated, have been detected in the oral cavity. Our purposes were (i) to utilize culture-independent molecular techniques to extend our knowledge on the breadth of bacterial diversity in the healthy human oral cavity, including not-yet-cultivated bacteria species, and (ii) to determine the site and subject specificity of bacterial colonization. [1]

Verrucous carcinoma of the oral cavity

A type of squamous carcinoma of the oral cavity, designated as verrucous carcinoma, has been described. This lesion occurs predominantly in aged men, most commonly on the buccal mucosa and lower gingiva. Tobacco chewing may be of etiologic significance. Slowly growing, well differentiated, verrucous in character, and often extensive, this neoplasm tends to invade local structures (mandible, soft tissues, antrum). No distant metastases occurred in the group reported, and local metastases were rare. Local recurrence is common with inadequately treated patients. Radiation is successful in controlling small superficial lesions. For extensive lesions, radical surgery is indicated and often when fixation, or invasion of bone is present, mandibular resection with upper neck dissection is justified. [2]

Saliva – the defender of the oral cavity

It is generally accepted that saliva is of paramount importance for the maintenance of oral health. This is based on the numerous studies reporting subjective and objective functional losses that occur in persons who lack the ability to produce adequate volumes of saliva. These include dry mouth feeling (xerostomia), difficulty with swallowing food, and an increased susceptibility for opportunistic infections.[3]

High Risk HPV Detected in Oral Cavity of Children in a Set Population of Karachi

Aims: The study was designed to determine the frequency of HPV in school going children and also find out cytopathological changes in the oral mucosa resulting from HPV infection.
Study Design: Cross sectional study.
Place and Duration of Study: Samples of oral rinse were collected from 300 healthy school going children (aged 5-18 years) during the period of March 2014 to June 2014 from two school campuses of Karachi (South) Pakistan. .[4]

Crosstalk between Mind and Oral Cavity: An Insight into Pathogenesis, Classification, Presentation and Management of Oral Psychosomatic Disorders

In general, the conviction is that psychological factors are important in the development of all disease. Epidemiological surveys have revealed that there are different ways in which emotional stressful stimuli can act on oral mucosal target sites. Whether their role is in initiation, progression, aggravation or exacerbation of disease or in predisposition or reaction to a disease is still not clear. Based on available evidences, a need for the understanding of oral psychosomatic disturbances is felt. This review summarizes the underlying pathophysiology of bodily changes brought about by stress related psychosomatic mechanism and their role in further development of structural changes seen in association with oral cavity. An effort has also been made to realize the significant.[5]



[1] Aas, J.A., Paster, B.J., Stokes, L.N., Olsen, I. and Dewhirst, F.E., 2005. Defining the normal bacterial flora of the oral cavity. Journal of clinical microbiology, 43(11), pp.5721-5732.

[2] Ackerman, L.V., 1948. Verrucous carcinoma of the oral cavity. Surgery23(4), pp.670-678.

[3] Amerongen, A.N. and Veerman, E.C.I., 2002. Saliva–the defender of the oral cavity. Oral diseases8(1), pp.12-22.

[4] Irshad, F., Baig, S., Syed, S. and Lucky, M.H., 2015. High Risk HPV Detected in Oral Cavity of Children in a Set Population of Karachi. International STD Research & Reviews, pp.27-32.

[5] Jain, K., Mehendiratta, M., Kardam, P., Yadav, J. and Jindal, D.G., 2016. Crosstalk between Mind and Oral Cavity: An Insight into Pathogenesis, Classification, Presentation and Management of Oral Psychosomatic Disorders. International Neuropsychiatric Disease Journal, pp.1-12.

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