News Update on Allergies: March – 2020

News Update on Allergies: March – 2020

International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods

The aetiology of asthma and allergic disease remains poorly understood, despite considerable research. The International Study of Asthma and Allergies in Childhood (ISAAC), was founded to maximize the value of epidemiological research into asthma and allergic disease, by establishing a standardized methodology and facilitating international collaboration. [1]

Diagnosing and Managing Common Food Allergies

Context There is heightened interest in food allergies but no clear consensus exists regarding the prevalence or most effective diagnostic and management approaches to food allergies. [2]

Farm environment in childhood prevents the development of allergies.

BACKGROUND:A protective effect of infections in early life might explain the firmly reported finding of an inverse association between atopic disorders and large sibships. OBJECTIVE:To study the effect of childhood farm, rural non-farm and urban environment, as well as family size and other factors on the occurrence of asthma, wheezing and atopic disorders up to young adulthood. METHODS:Data on lifetime prevalence of physician-diagnosed asthma, allergic rhinitis and/or allergic conjunctivitis, atopic dermatitis, as well as self-reported episodic wheezing from 10 667 Finnish first-year university students aged 18-24 years were collected by a postal questionnaire. [3]

A Phytotherapic Formulation for Allergic Rhinitis in Autistic Children

Aim: In this study, the efficacy of a nasal spray based on lemon pulp extract for the treatment of allergic rhinitis in autistic subjects was evaluated by nasal cytology. The lemon pulp extract was obtained using an innovative solid-liquid extraction technology using a Naviglio Extractor or a Rapid Solid-Liquid Dynamic Extractor (RSLDE) that extracts vegetable matrices from different species by using different types of solvents. Due to the pressurising and depressurising of this technique and using water as a solvent, it is possible to extract both the hydrophilic and lipophilic substances contained in vegetables in a heterogeneous solution.[4]

Anti-Allergic Action of Aqueous Extract of Moringa oleifera Lam. Leaves in Mice

Aims: The present investigation aimed to evaluate anti-allergic activity of an aqueous extract of Moringa oleifera Lam. leaves (AqMOL) in three type I allergy models in mice.

Study Design: Anti-allergic assay of AqMOL was performed using three type I allergy models in mice.

Place and Duration of Study: Department of Biochemistry, Graduate School of Clinical Pharmacy, Kyushu University of Health and Welfare, Nobeoka, Japan, from April 2014 to March 2015. [5]

 Reference

[1] Asher, M.I., Keil, U., Anderson, H.R., Beasley, R., Crane, J., Martinez, F., Mitchell, E.A., Pearce, N., Sibbald, B. and Stewart, A.W., 1995. International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. European respiratory journal8(3), pp.483-491.

[2] Chafen, J.J.S., Newberry, S.J., Riedl, M.A., Bravata, D.M., Maglione, M., Suttorp, M.J., Sundaram, V., Paige, N.M., Towfigh, A., Hulley, B.J. and Shekelle, P.G., 2010. Diagnosing and managing common food allergies: a systematic review. Jama303(18), pp.1848-1856.

[3] Kilpeläinen, M., Terho, E.O., Helenius, H. and Koskenvuo, M., 2000. Farm environment in childhood prevents the development of allergies. Clinical and experimental allergy: journal of the British Society for Allergy and Clinical Immunology30(2), pp.201-208.

[4] Ferrara, L., Caruso, A.A., Naviglio, D. and Gallo, M., 2014. A Phytotherapic Formulation for Allergic Rhinitis in Autistic Children. Advances in Research, pp.441-454.

[5]  Hagiwara, A., Hidaka, M., Takeda, S., Yoshida, H., Kai, H., Sugita, C., Watanabe, W. and Kurokawa, M., 2016. Anti-allergic action of aqueous extract of Moringa oleifera Lam. leaves in mice. European Journal of Medicinal Plants, pp.1-10.

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