Background: Hyperuricaemia is a risk factor for renal function deterioration that becomes more common as the estimated glomerular filtration rate (eGFR) stage proceeds.

The study’s goal is to talk about hyperuricemia and its consequences in patients with chronic noncommunicable diseases in a developing economy.

This retrospective study, which took place between January 2014 and December 2014, comprised 968 individuals with diabetes, hypertension, cardiovascular disease, and chronic renal disease. Glucose, serum uric acid, blood urea nitrogen, serum creatinine, lipid profile, liver enzymes, and albumin were all measured in each subject’s blood. Anthropometric indices such height, weight, waist circumference, age, gender, education, occupation, and medical history, including medications, were reported by each participant.

Patients with elevated serum uric acid (SUA) levels have a higher mean age, systolic blood pressure (SBP), SUA, blood urea nitogen (BUN), triglycerides, albumin, and very low density lipoprotein cholesterol (VLDL), as well as a lower mean estimated glomerular filtration rate (e-GFR) (P = 0.05) than patients with normal SUA levels. SUA has a strong relationship with e-GFR, BUN, serum creatinine, body mass index (BMI), waist circumference (WC), and albumin, according to correlation studies (p.0001). Uric acid levels are elevated in 223 (23.34 percent) of chronic kidney disease (CKD) patients, while they are normal in 745 (76.96 percent).

Conclusion: The long-established relationship between hyperuricemia and chronic renal disease is highlighted in this study. However, in order to avoid any trend toward an increase in serum uric acid levels in patients, the measures already in place in lifestyle clinics must be maintained.

Author(S) Details

Saleh Idris Tudun Wada
Department of Chemical Pathology, Faculty of Clinical Sciences, Bayero University, Kano, Nigeria.

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