News Release on Thrombosis Research: September-2018

Three-fold higher risk of cancer after acute thrombosis in the leg

Patients with the foremost acute form of occlusion within the leg — referred to as Associate in Nursing blood vessel occlusion — risk developing diseases that area unit way worse than the blood itself. the chance of developing cancer throughout the primary six months once the blood is 3 times larger than traditional.

This is shown by a register-based study that medical doctor and Ph.D. Jens Sundbøll has recently revealed within the journal Circulation. Jens Sundbøll is used at the Department of Clinical medical specialty, that is an element of the Department of Clinical drugs at urban center University and urban center University Hospital. [1]

Multiple Intracranial Aneurysms from Coccidioidal Meningitis: A Case Report Featuring Aneurysm Formation and Spontaneous Thrombosis with Literature Review

Background: Coccidioidal infectious disease will reach rubor with aneurysm formation. though aneurysmogenesis is rare, it carries exceptionally high mortality. Except in one instance, previous case reports have documented universally fatal consequences.

Case Description: A 26-year-old man developed disseminated coccidiomycosis with the formation of multiple aneurysms throughout the anterior intracranial vasculature bilaterally. This report is exclusive in this it chronicles the formation and ulterior spontaneous occlusion of many aneurysms over a 4-week amount. In total 10 aneurysms were documented within the same patient—the highest reported up to now. The patient was eventually discharged from the hospital for what has so far been a universally fatal unwellness method. medicine examination and tube imaging one month when discharging incontestable stable findings. [2]

Microbial Transplantation with Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential

Rationale: Gut microbes influence disorder (CVD) and occlusion risks through the assembly of trimethylamine N-oxide (TMAO). Microbiota-dependent generation of trimethylamine (TMA), the precursor to TMAO, is rate-limiting within the meta organismal TMAO pathway in most humans and is catalyzed by many distinct microbic vitamin B complex TMA-lyases, together with the proteins encoded by the choline-utilization C/D genes (cutC/D) in multiple human commensals. [3]

Ascites formation accompanied by portal vein thrombosis after porcine islet xenotransplantation via the portal vein in Rhesus macaque (Macaca mulatta)

Pig‐to‐nonhuman primate (NHP) islet transplantation has been widely conducted as a preclinical xenotransplantation model prior to human clinical trial. vein|portal|vena portae|vein|vena|venous blood vessel} occlusion is one among the complications related to isle infusion through the portal vein into the liver. Here, we briefly report a severe case of ascites formation accompanied by portal vein thrombi after pig‐to‐NHP islet xenotransplantation in a rhesus monkey. [4]

Headache Due to Cerebral Venous Thrombosis after Carbon monoxide Intoxication

Carbon monoxide; CO may be a colourless, odourless, tasteless and non-irritant style of gas. CO emerges as a consequence of poor combustion of carbon-based fuels, which might result in acute and chronic poisoning. Despite identical exposure conditions, people is also confronted with totally different symptoms of CO poisoning. There are not any qualitative studies on the long effects of CO poisoning on the headache, however there exist some reports of headache once chronic poisoning. the mix of cerebral blood vessel thrombosis; CVT with carbon monoxide intoxication has not been reported before. the foremost common symptom of patient’s admission for CVT was reported  as headache [6]. This rate has been reported  as between 77-88% in numerous studies. process swelling and optical atrophy once CO toxicity have usually been reported , however this case couldn’t be relating to increased  intracranial pressure. [5]

Reference

[1] Three-fold higher risk of cancer after acute thrombosis in the leg

Date: April 16, 2018, Source: Aarhus University (web link)

[2] Multiple Intracranial Aneurysms from Coccidioidal Meningitis: A Case Report Featuring Aneurysm Formation and Spontaneous Thrombosis with Literature Review

Buchanan IA, Ravina K, Strickland B, Fredrickson V, She R, Mathew A, Rennert R, Russin JJ. Multiple Intracranial Aneurysms from Coccidioidal Meningitis: A Case Report Featuring Aneury (web link)

[3] Microbial Transplantation with Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential

Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WW. Microbial Transplantation with Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. Circulation Research. 2018. (web link)

[4] Ascites formation accompanied by portal vein thrombosis after porcine islet xenotransplantation via the portal vein in Rhesus macaque (Macaca mulatta)

Kim JM, Shin JS, Han S, Min BH, Jeong WY, Lee GE, Kim MS, Kwon S, Chung H, Kang HJ, Park CG. Ascites formation accompanied by portal vein thrombosis after porcine islet xenotransplantation via the portal vein in Rhesus macaque (Macaca mulatta). Xenotransplantation. 2018. (web link)

[5] Headache Due to Cerebral Venous Thrombosis after Carbon monoxide Intoxication

  1. Tek got Uzuner1*, Y. Dinc1 and N. Uzuner1

1Department of Neurology, Eskisehir Osmangazi University, Eskisehir, Turkey.

(web link)