Ficus racemosa Stem Bark Extract: A Potent Antioxidant and a Probable Natural Radioprotector

Ethanol extract (FRE) and water extract (FRW) of genus Ficus racemosa (family: Moraceae) were subjected to atom scavenging each by steady state and time resolved ways like time unit pulse lysis and stopped-flow spectrophotometric analyses. FRE exhibited considerably higher steady state inhibitor activity than FRW. FRE exhibited concentration dependent DPPH, ABTS•-, radical and superoxide radical scavenging and inhibition of supermolecule peroxidation with IC50 comparable tested customary compounds. In vitro radioprotective potential of FRE was studied exploitation micronucleus assay in irradiated Chinese gnawing animal respiratory organ embryonic cell cells (V79). Pretreatment with totally different doses of FRE 1h before two Gy γ-radiation resulted during a vital (P < zero.001) decrease within the proportion of micronucleated binucleated V79 cells. most shelter was discovered at twenty μg/ml of FRE. [1]

Antiplasmodial compounds from Cassia siamea stem bark extract

Cassia siamea L. (Fabaceae) was known from the southwest Nigerian ethnobotany as a remedy for febrile  health problem. This junction rectifier to the bioassay‐guided fractionation of stem bark of the plant extract, victimisation the parasite feed dehydrogenase assay and multi‐resistant strain of Plasmodium falciparum (K1) for assessing the in vitro antiprotozoal drug activity. Emodin and lupeol were isolated from the ester fraction by a mix of natural action techniques. The structures of the compounds were determined by spectroscopic analysis, co‐spotting with authentic samples and comparison with literature knowledge. each compounds were found to be the active principles accountable for the antiplasmodial property with IC50 values of five µg/mL, severally. [2]

Qualitative phytochemical screening and in vitro antimicrobial effects of methanol stem bark extract of Ficus thonningii (Moraceae)

The methanolic stem bark extract of Ficus thonningii (Moraceae) was subjected to preliminary phytochemical screening and in vitro antimicrobial tests. The phytochemical tests was dispensed victimization commonplace strategies of study and these investigations discovered the presence of alkaloids, anthraquinones, carbohydrates, flavonoids, saponins and tannins. The antimicrobial activity of the plant extract was assayed victimization the agar plate disc diffusion and nutrient broth dilution techniques. take a look at small organisms were: Escherichia coli, enterobacteria spp, Pseudomonas aeruginosa, Salmonella typhi (Gram-negative), coccus aureus and eubacterium spp. (Grampositive). The extracts inhibited  the expansion of all the take a look at organisms at totally different concentrations particularly against Pseudomonas aeruginosa and eubacterium spp. that had mean inhibition zone of thirty three.33±7.33 metric linear unit and thirty two.33±2.51 metric linear unit severally. [3]

Ricinus communis L. stem bark extracts regulate ovarian cell functions and secretory activity and their response to Luteinising hormone

Ricinus communis L. has ethnopharmacological contraceptive name however its stem bark has undiscovered mechanisms of action in feminine system. within the gift study, the result of methanolic and binary compound extracts from the stem bark of the plant was examined on basic porcine sex gland granulosa cell functions and its response to Luteinising endocrine (LH)—the upstream secretion regulator. general treatment of methanolic and binary compound extracts stirred cell proliferation (proliferating cell nuclear substance, PCNA) and additionally promoted cell necrobiosis (caspase-3). binary compound extract has inverted the stimulatory result of LH on PCNA however not on caspase-3. Methanolic extract stirred still as stifled progestin unharness and stimulated androgenic hormone secretion. [4]

Preliminary Phytochemical Screening and Antiviral Potential of Methanol Stem Bark Extract of Enantia chlorantha Oliver (Annonaceae) and Boswellia dalzielii Hutch (Burseraceae) against Newcastle Disease In Ovo

Aim of the Study: to work out the phytochemicals and also the antiviral activity of methyl alcohol stem bark extract of Enantia chlorantha and genus Boswellia dalzielii against animal disease virus in embryonated eggs.

Materials and Methods: Preliminary phytochemical screening was disbursed exploitation normal ways. Investigation on the impact of stem bark of Enantia chlorantha Associate in Nursingd genus Boswellia dalzielii methyl alcohol  extracts against animal disease (ND) virus was disbursed exploitation an in ovo assay. Nine–day-old embryonated chicken eggs were used. 0.2ml New Castle illness virus (NDV) pre-treated with methyl alcohol extract of Enantia chlorantha Oliver and genus Boswellia dalzielii Hutch (Stem bark) at final concentrations of one hundred fifty, 100, 50, 25, 12.5 mg/ml were administered. Controls were enclosed, embryos were discovered daily for survival. fetal membrane fluids from treated eggs were collected for spot take a look at and hemagglutination take a look at to observe NDV within the eggs. [5]

Reference

[1] Veerapur, V.P., Prabhakar, K.R., Parihar, V.K., Kandadi, M.R., Ramakrishana, S., Mishra, B., Rao, S., Srinivasan, K.K., Priyadarsini, K.I. and Unnikrishnan, M.K., 2009. Ficus racemosa stem bark extract: a potent antioxidant and a probable natural radioprotector. Evidence-Based Complementary and Alternative Medicine, 6(3), (Web Link)

[2] Ajaiyeoba, E.O., Ashidi, J.S., Okpako, L.C., Houghton, P.J. and Wright, C.W., 2008. Antiplasmodial compounds from Cassia siamea stem bark extract. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 22(2), (Web Link)

[3] Usman, H., Abdulrahman, F.I. and Usman, A., 2009. Qualitative phytochemical screening and in vitro antimicrobial effects of methanol stem bark extract of Ficus thonningii (Moraceae). African Journal of Traditional, Complementary and Alternative Medicines, 6(3). (Web Link)

[4] Ricinus communis L. stem bark extracts regulate ovarian cell functions and secretory activity and their response to Luteinising hormone
S Nath, A Kadasi, R Grossmann, A V Sirotkin, A Kolesarova, A D Talukdar & M D Choudhury
International Journal of Impotence Research volume 27, (Web Link)

[5] Ohemu, T. L., Agunu, A., C. Chollom, S., Okwori, V. A., G. Dalen, D. and N. Olotu, P. (2018) “Preliminary Phytochemical Screening and Antiviral Potential of Methanol Stem Bark Extract of Enantia chlorantha Oliver (Annonaceae) and Boswellia dalzielii Hutch (Burseraceae) against Newcastle Disease In Ovo”, European Journal of Medicinal Plants, 25(4), (Web Link)

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