Vitiligo and Thyroid Autoimmunity

Vitiligo and Thyroid Autoimmunity

Vitiligo is an acquired skin disorder characterized by depigmented maculae resulting from a reduction or the number and function of melanocytes. It is characterized by macular depigmentation of varying sizes or shapes with a tendency to progress. The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity and endocrine dysfunction may be involved. Vitiligo has been reported in association with numerous endocrine disorders. One of the main association is with thyroid abnormalities. Thyroid autoimmunity is the most prevalent autoimmune condition in the general population, and is also associated with various skin diseases. The mechanisms by which these diseases develop are unknown, although it is likely that diseases occur in genetically susceptible individuals exposed to a permissive environment.  This chapter is an attempt to update the current knowledge about the relationship between vitiligo and thyroid autoimmunity. Although cutaneous manifestation of autoimmune thyroid diseases are well described, a better understanding of these processes is needed. It is a multidisciplinary problem requiring cooperation of specialist in different fields of medicine. Both dermatologist and endocrinologists have to inquire their patients about the family history of autoimmune diseases and to look for associated disorders.

Author(s) Details

 Emina Kasumagic-Halilovic
Department of Dermatovenereology, Clinical Center University of Sarajevo, Bosnia and Herzegovina.

Nermina Ovcina-Kurtovic
Department of Dermatovenereology, Clinical Center University of Sarajevo, Bosnia and Herzegovina.

View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/178

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