News Release on Infectious Diseases Research: August-2018

News Release on Infectious Diseases Research: August-2018

News Release on Infectious Diseases Research: August-2018

New approach to treating infectious diseases as an alternative to antibiotics

Researchers have processed however morbific E. coli bacterium hooked up to the host viscus animal tissue. They disclosed that kind IV pili on the surface of the bacterium weren’t adequate for adherence to viscus animal tissue cells which proteins secreted by E.coli were conjointly necessary. it had been found that this attachment mechanism could be a typical feature in several enteropathogens akin to eubacteria Asiatic cholera and constitutes a unique therapeutic target against such microorganism pathogens. [1]

Infectious diseases acquired by international travellers visiting the USA

Background: Estimates of travel-related malady have centered preponderantly on populations from extremely developed countries visiting low- or middle-income countries, nevertheless visit and among high-income countries is incredibly frequent. Despite being a high international traveller destination, few sources describe the spectrum of infectious diseases noninheritable  among travellers to the USA. [2]

The use of sulfonamides in the pharmacotherapy of infectious diseases of humans and animals and the associated environmental risk

Sulfonamides square measure one in all the oldest medicine medicine that stay still in use in humans and animals treatment. These compounds block the synthesis of vitamin B complex in microorganism cells, therefore inhibiting growth of bacterium. so as to raise the medical specialty activity, sulfonamides square measure typically combined with trimethoprim. The role of these organic process agents has diminished over the years, primarily because of increasing microorganism resistance that is a control of the inappropriate use of sulfonamides. There square measure still many compounds that square measure administered in humans to treat not solely microorganism infections, however conjointly protozoan ones (e.g. toxoplasmosis), as an example Gantanol, sulpha, sulfathiazole. additional variety of sulfonamides is employed in veterinary. [3]

Role of Infectious Diseases in the Antiphospholipid Syndrome (Including Its Catastrophic Variant)

Purpose of Review: The antiphospholipid syndrome (APS) is characterised by the event of thrombotic events and gestation morbidity within the presence of antiphospholipid antibodies (aPL). AN infectious etiology for this syndrome has been postulated. this review is aimed to summarize recent proof regarding the role of infections and vaccines within the pathological process of the APS (including its harmful variant). [4]

A New Superagglutination Test to Minimize False Negative and False Positive Results Common with Plate/Slide Agglutination Tests for the Diagnosis of Infectious Diseases

Agglutination is that the clumping of matter particles by antibodies. many diagnostic kits for infectious diseases of animals and humans, supported slide agglutination/plate agglutination tests just like the Rose Bengala|geographic area|geographical region|geographic region} Plate take a look at (RBPT) for identification of brucellosis are used worldwide. False negative and false positive results area unit unremarkably encountered in these typical agglutination tests. Simple, price effective modifications will facilitate in circumventing these issues. The novel Superagglutination take a look at reported  here may be a changed slide / plate blood test. False negative results thanks to smaller clumps shaped by low titre of antibodies in body fluid area unit reduced by the addition of biotinylated antiglobulin followed by Avidin that forms simply detectable larger clumps. Similarly, previous staining of body fluid antibodies with a dye helps in differentiating a particular agglutinate shaped by each matter and protein, from a non-specific combination of matter alone that results in false positive results. Superagglutination is additional sensitive than this agglutination tests and agglutination primarily based diagnostic kits. [5]

Reference

[1] New approach to treating infectious diseases as an alternative to antibiotics

Date: July 11, 2018, Source: Osaka University (web link)

[2] Infectious diseases acquired by international travellers visiting the USA

Stoney RJ, Esposito DH, Kozarsky P, Hamer DH, Grobusch MP, Gkrania-Klotsas E, Libman M, Gautret P, Lim PL, Leder K, Schwartz E. Infectious diseases acquired by international travellers visiting the USA. Journal of travel medicine. 2018 Aug 17;25(1):tay053. (web link)

[3] The use of sulfonamides in the pharmacotherapy of infectious diseases of humans and animals and the associated environmental risk

Podkowa A, Włodarczyk A, Opoka W, Muszyńska B. The use of sulfonamides in the pharmacotherapy of infectious diseases of humans and animals and the associated environmental risk. Medicina Internacia Revuo-International Medicine Review. 2018 Aug 17;28(110):4-10. (web link)

[4] Role of Infectious Diseases in the Antiphospholipid Syndrome (Including Its Catastrophic Variant)

Mendoza-Pinto C, García-Carrasco M, Cervera R. Role of Infectious Diseases in the Antiphospholipid Syndrome (Including Its Catastrophic Variant). Current rheumatology reports. 2018 Oct 1;20(10):62. (web link)

[5] A New Superagglutination Test to Minimize False Negative and False Positive Results Common with Plate/Slide Agglutination Tests for the Diagnosis of Infectious Diseases

Hari Mohan Saxena1* and Paviter Kaur1

1Department of Veterinary Microbiology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, India. (web link)

Editor 251News

leave a comment

Create Account



Log In Your Account



WP2Social Auto Publish Powered By : XYZScripts.com