Newsletter on Immunology Research: August-2018

Why Women Have Stronger Immune Systems than Men

Women not solely live longer than men, they conjointly seem to be in additional strong health. a brand new hypothesis offers a reason why: it’s in their genes.

Women ar celebrated to own a lower incidence of cancer — men have a two- to five-fold larger risk of developing the illness. girls are higher able to survive trauma, and, in line with some reports, do not get as seriously unwell from microorganism and microorganism infections.

In a new paper, researchers from city University in Belgium argue these sex-specific health disparities could also be due, a minimum of partly, to small items of genetic material known as microRNAs. the most operate of microRNAs in cells is to show off, or “silence,” specific genes. The researchers say microRNAs situated on the feminine X chromosome might provide girls AN system advantage over males. [1]

A proposal for input classification for inventory management in the biopharmaceutical industry. Study case in the Molecular Immunology Center

The emergence of the biotechnological sector started a revolution within the ancient competitive basis of the pharmaceutical industries, in terms of development and manufacture of merchandise, particularly those geared toward human health. Inventory management during this trade is incredibly advanced, with varied, high-volume inventories, given the quality of capital punishment 2 processes that have a sway on inventory management: production, and R&D. The quality of those processes demands a supplying system with the capability and suppleness to adapt to the various totally different rules alive and changes in sales plans, associated an science resolution that enables integration of the various elements of the system. this article aims to judge the case of Inventory Management at the Molecular medical specialty Center from the implementation of the ideas of Project Input and method Input. The analysis was applied through numerous strategies and tools as well as listing analysis, knowledgeable interviews, record querying, and group action. [2]

Effects of Bacillus amyloliquefaciens and Yarrowia lipolytica lipase 2 on immunology and growth performance of Hybrid sturgeon

A 12-weeks feeding trial was performed to investigate the possible effects of supplementation of Hybrid sturgeon diet with Bacillus amyloliquefaciens (GB-9) and Yarrowia lipolytica lipase2 (YLL2) single or combined on immune response and growth performance of Hybrid sturgeon (Acipenser schrenkii ♂and Acipenser baeri ♀). For this aim, Hybrid sturgeons were fed with four experimental diets namely: Diet one (0-control), Diet 2 (5.0 g/kg GB-9), Diet 3 (4.0 g/kg YLL2), and Diet four (5.0 g/kg GB-9 + four.0 g/kg YLL2), severally. when fed with varied diets, growth performance, tissue layer response, leukocytes response and blood serum medical specialty response were measured. [3]

Correlation between C-reactive protein level, immunology, and hematology of a Oncorhynchus mykiss infected with Lactococcus garvieae

The aim of this experiment was to guage the symptoms, variation, and correlation of haematological factors and a few parameters of the innate response of the infected rainbow trout (Oncorhynchus mykiss) fish with Lactococcus garvieae microorganism. a complete of 270 fish were divided into 3 teams as well as infected fish with a high and low concentration of L. garvieae and an effect cluster while not infection. The blood and tissue (brain, head, kidney, and spleen) samples were collected from each group (n = 6 fish) at 0, 3, 14, and twenty one days when treatment. the foremost discovered symptoms throughout infection were lethargy, exophthalmia, and pathology. The mortality rates for the high and low dose-infected fish were outlined as sixty and twenty fifth, severally. [4]

Modulation of Immunological and Hematological Disturbances of Diabetes Mellitus by Diets Containing Combined Leaves of  Vernonia amygdalina and Gongronema latifolium

Background: medicine and hematologic alterations usually occur in diabetes as a results of aerobic  stress. This study investigated the consequences of consumption of diets containing herb amygdalina leaves on some markers of medicine and medical specialty in Streptozotocin -induced diabetic wistar rats with the read to evaluating its involvement within the management of medicine and hematologic complications among diabetics.

Method: the planning consisted of eighty rats haphazardly divided into eight teams of ten rats per cluster. Groups 2, 3, 4, 5, 6,7 and eight were diabetic, whereas cluster one was traditional management. teams one and a couple of were fed with management diet. cluster three to seven were fed with diets containing herb amygdalina, or Gongronema latifolium or combined leaves of herb amygdalina and Gongronema latifolium. cluster eight was fed with the management diet however treated with hormone. Feed and water got ad- libitum for twenty eight days.

Results: Results showed that diabetic rats overwhelming diets of herb amygdalina, Gongronema latifolium leaves or the combined leaves diets all had vital (P<0.05) increase within the red somatic cell (RBC), hemoglobin, and white blood corpuscle counts relative to the diabetic management. All the diets resulted in vital (P<0.05) reduction within the level of white somatic cell (WBC), platelets, neutrophil, and CD4+ cell count relative to the diabetic management. [5]

 

Reference

[1] Why Women Have Stronger Immune Systems than Men

By Livescience.com, staff , (web link)

[2] A proposal for input classification for inventory management in the biopharmaceutical industry. Study case in the Molecular Immunology Center

Domínguez-Pérez F, Lopes-Martínez I, Felipe-Valdés PM, Vallin-García AE, Cruz-Ruiz A. A proposal for input classification for inventory management in the biopharmaceutical industry. Study case in the Molecular Immunology Center. VacciMonitor. 2018;27(2):51-60. (web link)

[3] Effects of Bacillus amyloliquefaciens and Yarrowia lipolytica lipase 2 on immunology and growth performance of Hybrid sturgeon

Fei H, Lin GD, Zheng CC, Huang MM, Qian SC, Wu ZJ, Sun C, Shi ZG, Li JY, Han BN. Effects of Bacillus amyloliquefaciens and Yarrowia lipolytica lipase 2 on immunology and growth performance of Hybrid sturgeon. Fish & shellfish immunology. 2018 Aug 17. (web link)

[4] Correlation between C-reactive protein level, immunology, and hematology of a Oncorhynchus mykiss infected with Lactococcus garvieae

Khosravi M, Mohammadian T, Tahmasebifard M, Boroujeni MP. Correlation between C-reactive protein level, immunology, and hematology of a Oncorhynchus mykiss infected with Lactococcus garvieae. Aquaculture International. 2018:1-1. (web link)

[5] Modulation of Immunological and Hematological Disturbances of Diabetes Mellitus by Diets Containing Combined Leaves of  Vernonia amygdalina and Gongronema latifolium

Henry D. Akpan1* and Itemobong Ekaidem2

1Department of Biochemistry, Faculty of Basic Medical Sciences, University of Uyo, Uyo, Nigeria.

2Department of Chemical Pathology, Faculty of Clinical Sciences, University of Uyo, Uyo, Nigeria. (web link)