Press Release on Ebola Virus Research: September-2018

Potent antibodies against three Ebola viruses

Researchers at Commodore Vanderbilt University middle and their colleagues’ are a step nearer to developing a broadly speaking effective protein treatment against the 3 major VHF viruses that cause fatal sickness in humans.

Reporting Gregorian calendar month seventeen within the journal Immunity, they describe the isolation of 2 potent organism antibodies from human survivors of Ebola virus sickness that, in cell culture studies, with efficiency neutralized the Zaire, Sudan and Bundibugyo ebolaviruses. [1]

Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

Background: filovirus (EBOV) primarily targets myeloid cells; but, the in-depth death of T cells is commonly determined in fatal infections. we’ve got antecedently shown that EBOV VP40 in exosomes causes recipient immune death.

Methods: mistreatment VP40-producing clones, we have a tendency to analyzed donor cell cycle, animate thing cyst (EV) biogenesis, and recipient immune death. Transcription of cyclin D1 and nuclear localization of VP40 were examined via enzyme and chromatin granule immunoprecipitation assays. [2]

China in the Fight Against the Ebola Crisis: Human Security Perspectives

The occurrence of the Ebola virus illness (EVD) in West Africa became one in every of the worst disease-driven humanitarian crises in fashionable history. The crisis turned the world securitization of health problems into new levels, at the identical time, aligned closely with human security frameworks and so has important impacts on national foreign and aid policies. China has vied a big role in the international fight against Ebola fever, indicating vital changes in its policy orientations. [3]

Ebola: Etiology, Prevention, and Treatment by Herbal Remedies

Ebola virus is that the single member of the species Zaire filovirus, that is that the species for the genus filovirus, family, order Mononegavirales. The natural reservoir of filovirus is believed to be bonkers, significantly fruit bonkers, and it’s primarily transmitted between humans and from animals to humans through body fluids. The filovirus contains a high death rate, with a current case mortality rate calculable to be around five hundredths. Mortality rates for previous outbreaks have varied from twenty-fifth to ninetieth, and people outbreaks are comparatively passing (WHO, 2014) seen close to the tropical rainforests of remote villages in the Central and geographical area. it unfolds by shut contact with patients or exposure to infected biological fluids. [4]

How the Spread of Ebola Virus was Curtailed in Nigeria

Ebola virus, the motivative agent of Ebola virus unwellness (EVD) once referred to as hemorrhagic fever virus infection (EHF) is one of the foremost dangerous microorganisms within the world. The virus ravaged geographic area countries significantly, Guinea, Republic of Sierra Leone and the Republic of Liberia infecting over twenty-two,000 people, of that nearly five-hundredths resulted in fatalities. once the unwellness finally reached metropolis on twenty Gregorian calendar month 2014, it brought worry and panic owing to the massive population of a metropolis and therefore the chaotic socio-economic scenario as well as dysfunctional health that was even on strike at the time of the natural event. Also, there was no approved medical specialty and preventive vaccinum. [5]

Reference

[1] Potent antibodies against three Ebola viruses

Date: July 30, 2018, Source: Vanderbilt University Medical Center (web link)

[2] Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

Pleet ML, Erickson J, DeMarino C, Barclay RA, Cowen M, Lepene B, Liang J, Kuhn JH, Prugar L, Stonier SW, Dye JM. Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles. The Journal of Infectious Diseases. 2018 Aug 30. (web link)

[3] China in the Fight Against the Ebola Crisis: Human Security Perspectives

Cui S. China in the Fight Against the Ebola Crisis: Human Security Perspectives. InHuman Security and Cross-Border Cooperation in East Asia 2019 (pp. 155-180). Palgrave Macmillan, Cham. (web link)

[4] Ebola: Etiology, Prevention and Treatment by Herbal Remedies

Jain SD, Birla DK, Mishra D. Ebola: Etiology, Prevention and Treatment by Herbal Remedies. PharmaTutor. 2018 Sep 1;6(9):20-3. (web link)

[5] How the Spread of Ebola Virus was Curtailed in Nigeria

Elijah I. Ohimain1,2,3*

1Department of Biological Sciences, Medical and Public Health Microbiology Research Unit, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.

2Department of Biological Sciences, Bioenergy and Environmental Biotechnology Research Unit, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria.

3Department of Biological Sciences, Microbial Ecology Laboratory, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria. (web link)