A off-course variety of subordinate metabolites are produced by plants as a kind of care against environmental stress or different causes like pest infestations, wounds, and injuries. Pulse crops have a long experiences of being valued for their digestive value and strength-promoting qualities, containing their outstanding protein, fibre, and oxygen content as well as their ability to control obesity, decrease cholesterol, and hamper type 2 diabetes.In this book chapter, I have discussed about the antihyperglycemic potential of Cajanus cajan leaves indifferent solvent extracts on alloxan-persuaded diabetic mice. Among the four stable extracts tested, namely oil ether, kill, ethyl acetate, and methanol extract, two extracts, i.e ethyl acetate and flammable liquid extract, lowered level of glucose in blood levels by 27.09 and 37.68%, respectively, in diabetic rodent after daily spoken administration for 10 days at a dosage of 250 mg/kg. Glibenclamide (0.4mg/kg) reduced blood sugar levels by 30.57% all along the same situation period. These two extracts also raised insulin action. While insulin unique resulted in a 32.66% decrease in glucose. Blood sugar dropped by 48.14% and 43.07%, respectively, afterwards the extract of methanol and ethyl acetate were executed simultaneously. The extract did not exhibit some fatality or poisonous symptoms at a measurement of 2000 mg/kg in an acute toxicity trial (OECD recommendations), and by way of, C. cajan extracts are regarded as dependable. The active fractions’ RP-HPLC characterizations were completed; these sketches will be useful in the future for labeling the bioactive elements.
Girijananda Chowdhury University, Guwahati, Assam, India.
Please see the link here: https://stm.bookpi.org/COPS-V8/article/view/9874
Keywords: Cajanus cajan, antihyperglycemic activity, alloxan, acute toxicity, antidiabetic plants