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The rapid development of surface sensitive biosensor technologies requires optimum control of surface modification to provide reliable and reproducible results. To assemble a quartz crystal microbalance (QCM)-based protein biosensor, we focused our attention on the sulfide receptor and its integration with the surface of the golden electrode. Here, we present different surface modification processing time to allow sulfide molecules to be immobilized to a gold-coated sensor for QCM sensing. The surface modification was also tested with bovine serum albumin (BSA) binding measurement. The optimum surface modification processing time was obtained according to the experiment.
Author(s) Details
Yu-Cheng Lin
Graduate Institute of Electronic Engineering, Ming Chung University, Taoyuan, Taiwan
Yi-Chi Chen
R&D department, Ampire Co. Ltd., New Taipei City, Taiwan
Liang-Yu Chen
Graduate Institute of Biological Technology, Ming Chung University, Taoyuan, Taiwan.
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