Surface Modification of Sulfide for QCM Based Protein Biosensor

The rapid development of surface sensitive biosensor technologies requires optimum control of surface modification to provide reliable and reproducible results. To assemble a quartz crystal microbalance (QCM)-based protein biosensor, we focused our attention on the sulfide receptor and its integration with the surface of the golden electrode. Here, we present different surface modification processing time to allow sulfide molecules to be immobilized to a gold-coated sensor for QCM sensing. The surface modification was also tested with bovine serum albumin (BSA) binding measurement. The optimum surface modification processing time was obtained according to the experiment.

Author(s) Details

Yu-Cheng Lin
Graduate Institute of Electronic Engineering, Ming Chung University, Taoyuan, Taiwan

Yi-Chi Chen
R&D department, Ampire Co. Ltd., New Taipei City, Taiwan

Liang-Yu Chen
Graduate Institute of Biological Technology, Ming Chung University, Taoyuan, Taiwan.

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